HedgehogHedgehog ligands (Sonic Indian and Desert hedgehog) are morphogens that signal through Patched Smoothened and Gli to pattern organ development. Notably during gastrulation Indian Hedgehog (Ihh) signaling from the visceral endoderm has been deemed necessary and suffi cient for blood formation in the murine yolk sac 98 99 .
2021-5-21 · The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation.Different parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the malfunction of this pathway include basal cell carcinoma.
2015-6-1 · Description Lipoprotein particles are required for Hedgehog and Wingless signalling Daniela Pana´kova´ Hein Sprong † Eric Marois Christoph Thiele Suzanne Eaton
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