2013-6-25 · f Inhaling Bis(2-Ethylhexyl) Phthalate can irritate the nose and throat. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Bis(2-Ethylhexyl) Phthalate and can last for months or years Cancer Hazard f Bis(2-Ethylhexyl) Phthalate may be a CARCINOGEN in
2020-10-5 · phthalates such as di-2-(ethylhexyl) phthalate (DEHP). DEHP is a high production volume chemical associated with metabolic and immune disruption in animals and humans. To reveal mechanisms implicated in phthalate-related disruption in the gastrointestinal system male and zebrafish were fed DEHP (3 ppm) daily for two months.
such as bis(2-ethylhexyl) phthalate DEHP a common polyvinyl chloride (PVC) additive dibutyl phthalate (DBP) and butyl benzyl phthalate (BBP) and also lower-molecular-weight phthalates such as dimethyl phthalate (DMP) and diethyl phthalate (DEP) which is commonly used as a solvent for fragrance. All of these are used in food packaging.
Bis(2-ethylhexyl) Phthalate. text.skipToContent text.skipToNavigation. TCI uses cookies to personalize and improve your user experience. By continuing on our website you accept the use of cookies. You can change or update your cookiesettings at any time. Accept. Welcome to TCI s new website
2015-6-11 · Bis(2-ethylhexyl)phthalate (Water Source) Page 4 of 5 Cattley R.C. J.G. Conway and J.A. Popp. 1987. Association of persistent peroxisome proliferation and oxidative injury with hepatocarcinogenicity in F-344 rats fed di(2-ethylhexyl)phthalate. Cancer Letters. 38 15-22. CHAP (Chronic Hazard Advisory Panel on Di(2-ethylhexyl)phthalate
such as bis(2-ethylhexyl) phthalate DEHP a common polyvinyl chloride (PVC) additive dibutyl phthalate (DBP) and butyl benzyl phthalate (BBP) and also lower-molecular-weight phthalates such as dimethyl phthalate (DMP) and diethyl phthalate (DEP) which is commonly used as a solvent for fragrance. All of these are used in food packaging.
1999-6-1 · Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate Jpn. J. Cancer Res. (Gann) 81 ( 1990 ) pp. 213215
2013-6-25 · f Inhaling Bis(2-Ethylhexyl) Phthalate can irritate the nose and throat. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Bis(2-Ethylhexyl) Phthalate and can last for months or years Cancer Hazard f Bis(2-Ethylhexyl) Phthalate may be a CARCINOGEN in
Di(2-ethylhexyl) phthalate (DEHP) / bis (2-ethylhexyl) benzene-1 2- dicarboxylate MAK Value Documentation A. Hartwig1 MAK Commission2 DOI 10.1002/3527600418.mb11781e6017 Abstract The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the developmental toxicity of di(2
2015-6-11 · Bis(2-ethylhexyl)phthalate (Water Source) Page 4 of 5 Cattley R.C. J.G. Conway and J.A. Popp. 1987. Association of persistent peroxisome proliferation and oxidative injury with hepatocarcinogenicity in F-344 rats fed di(2-ethylhexyl)phthalate. Cancer Letters. 38 15-22. CHAP (Chronic Hazard Advisory Panel on Di(2-ethylhexyl)phthalate
Di(2-ethylhexyl)phthalate (DEHP) is also known as 1 2-benzenedicarboxylic acid bis(2-ethylhexyl)ester bis(2-ethylhexyl) phthalate and dioctyl phthalate (DOP). Physicochemical properties (1 2) Conversion factor in air 1 ppm = 1.59 mg/m3 Property Value Physical state Light-coloured viscous liquid Melting point -46 °C (pour-point)
2008-7-18 · use in anti-cancer agent of bis-(2-ethylhexyl) phthalate (patkr20100009364) ahn joong hoon lim yoong ho chong you hoon hong sung won lee young han shin soon young yong yeon joong kang kyung rai koo bon sung
Bis (2-ethylhexyl) phthalate ( di-2-ethylhexyl phthalate diethylhexyl phthalate DEHP dioctyl phthalate DOP) is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. DEHP is the most common member of the class of phthalate s which are used as plasticizers.
2018-2-22 · Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products especially medical devices furniture materials cosmetics and personal care products. DEHP is noncovalently bound to plastics and therefore it will leach out of these products after repeated use heating and/or cleaning of the products. Due to the overuse of DEHP in many products it enters and
Bis(2-ethylhexyl) phthalate is a phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1 2-dicarboxylic acid. It has a role as an apoptosis inhibitor an androstane receptor agonist and a plasticiser. It is a phthalate ester and a diester.
Hexyl 2-ethylhexyl phthalate C22H34O4 CID 156626structure chemical names physical and chemical properties classification patents literature biological activities safety/hazards/toxicity information supplier lists and more.
2020-12-10 · Di (2-ethylhexyl) phthalate is a liquid of low volatility widely used as a plasticizer in flexible poly (vinyl chloride) products at concentrations of up to 40 as well as in a number of other minor applications. Occupational exposure occurs mainly by inhalation as an aerosol during its manufacture and its use as a plasticizer in poly (vinyl
Background Bisphenol A (BPA) and bis(2-ethylhexyl) phthalate (DEHP) are high-production-volume chemicals used in plastics and resins for food packaging. They have been associated with endocrine disruption in animals and in some human studies.
2013-6-25 · f Inhaling Bis(2-Ethylhexyl) Phthalate can irritate the nose and throat. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Bis(2-Ethylhexyl) Phthalate and can last for months or years Cancer Hazard f Bis(2-Ethylhexyl) Phthalate may be a CARCINOGEN in
2018-6-28 · phthalate phthalic acid bis(2-ethylhexyl) DI(2-ETHYLHEXYL) PHTHALATE This substance was considered by previous Working Groups in October 1981 (IARC 1982) March 1987 (IARC 1987) and February 2000 (IARC 2000). Since that time new data have become available and these have been incorporated into the
Bis (2-ethylhexyl) phthalate ( di-2-ethylhexyl phthalate diethylhexyl phthalate DEHP dioctyl phthalate DOP) is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. DEHP is the most common member of the class of phthalate s which are used as plasticizers.
Di(2-ethylhexyl) phthalate (DEHP) / bis (2-ethylhexyl) benzene-1 2- dicarboxylate MAK Value Documentation A. Hartwig1 MAK Commission2 DOI 10.1002/3527600418.mb11781e6017 Abstract The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the developmental toxicity of di(2
2020-6-4 · Introduction. Exposure to persistent environmental pollutants such as phthalate has been linked to the induction of multiple human pathologies including diabetes and cancer (Sun et al. 2015).Once utilized extensively as plasticizers to impart flexibility transparency and durability of plastic materials the production of phthalate including di(2-ethylhexyl) phthalate (DEHP) was banned in the
2011-12-15 · Preliminary studies from our laboratory revealed that bis(2-ethylhexyl) phthalate (DEHP) is a possible EDC which induces cell proliferation in T47D MCF7 MCF7/Aro breast cancer cells in vitro and confers insensitivity to letrozole a third generation aromatase inhibitor.
Bis(2-ethylhexyl) phthalate. Molecular Formula C 24 H 38 O 4 Average mass 390.556 Da Monoisotopic mass 390.277008 Da ChemSpider ID 21106505
2018-12-12 · Di-(2-ethylhexyl) phthalate1 of 13 Toxicological Summary for Di-(2-ethylhexyl) phthalate CAS 117-81-7 Health Based Guidance for Water Health Risk Assessment Unit Environmental Health Division 651-201-4899 . Adopted as Rule November 2015 . Synonyms DEHP Bis(2-ethylhexyl)phthalate . Acute Non-Cancer Health Risk Limit (nHRL. Acute) = 20 µg/L
1999-6-1 · Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate Jpn. J. Cancer Res. (Gann) 81 ( 1990 ) pp. 213215
Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men. Environ Health Perspect 115 1029-1034 17637918. Link Google Scholar Meeker JD Calafat AM Hauser R. 2009. Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men. J Androl 30 287-297 19059903.
2016-1-13 · Acute EPA has found di (2-ethylhexyl) phthalate (DEHP) to potentially cause the following health effects from acute exposures at levels above the MCL mild gastrointestinal disturbances nausea vertigo. Chronic DEHP has the potential to cause the following health
2018-6-28 · phthalate phthalic acid bis(2-ethylhexyl) DI(2-ETHYLHEXYL) PHTHALATE This substance was considered by previous Working Groups in October 1981 (IARC 1982) March 1987 (IARC 1987) and February 2000 (IARC 2000). Since that time new data have become available and these have been incorporated into the
DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.Mechanism of Action Protocol.
1999-6-1 · Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate Jpn. J. Cancer Res. (Gann) 81 ( 1990 ) pp. 213215
Bis(2-ethylhexyl) phthalate (DEHP) is a compound widely used in plastics technology to impart flexibility to rigid polymers. We sought to determine whether the oral exposure of rats to DEHP during gestation and suckling produces alterations in the litter. rats were exposed to different concentrations of DEHP suspended in drinking water (32.5 and 325 microl/litre) from day 1 of
1999-6-1 · Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate Jpn. J. Cancer Res. (Gann) 81 ( 1990 ) pp. 213215
2021-6-25 · Bis(2-ethylhexyl) phthalate (DEHP) is used in the production of polyvinyl chloride (PVC). It exhibits lowtoxicity from acute (short-term) and chronic (long-term) exposures. Acute exposure to large oral doses ofDEHP can cause gastrointestinal distress in humans. No information is available on the chronic reproductive developmental or carcinogenic effects of DEHP in humans. Animal studies have reportedincreased lung weights and increased liver weights from chronic inhalation exposure to DEHP. Oralexposure has resulted in developmental and reproductive effects in rats and mice. A study by the NationalToxicology Program (NTP) showed that DEHP administered orally increased the incidence of liver tumors inrats and mice. EPA has classified DEHP
2011-12-15 · Preliminary studies from our laboratory revealed that bis(2-ethylhexyl) phthalate (DEHP) is a possible EDC which induces cell proliferation in T47D MCF7 MCF7/Aro breast cancer cells in vitro and confers insensitivity to letrozole a third generation aromatase inhibitor.
The current United States Environmental Protection Agency (EPA) classification of di(2-ethylhexyl)phthalate (DEHP) as a B2 "probable human" carcinogen is based on outdated information. New toxicology data and a considerable amount of new mechanistic evidence were used to reconsider the cancer classification of DEHP under EPA s proposed new cancer risk assessment guidelines.
("Wallets") containing Bis (2-ethylhexyl) phthalate ("DEHP") also known as Di (2-ethylhexyl) phthalate. On January 1 1988 the Govemor of Califomia added DEHP to the list of chemicals known to the State to cause cancer and on October 24 2003 the Govemor added DEHP to the list of 1
2020-12-10 · Di (2-ethylhexyl) phthalate is a liquid of low volatility widely used as a plasticizer in flexible poly (vinyl chloride) products at concentrations of up to 40 as well as in a number of other minor applications. Occupational exposure occurs mainly by inhalation as an aerosol during its manufacture and its use as a plasticizer in poly (vinyl
Di(2-ethylhexyl) phthalate (DEHP) / bis (2-ethylhexyl) benzene-1 2- dicarboxylate MAK Value Documentation A. Hartwig1 MAK Commission2 DOI 10.1002/3527600418.mb11781e6017 Abstract The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re-evaluated the developmental toxicity of di(2
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